RES
1b:o-dgal-HEX-0:0|1:aldi
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:b-dglc-HEX-1:5
5s:n-acetyl
6b:b-dgal-HEX-1:5
7s:sulfate
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:1o(6+1)4d
4:4d(2+1)5n
5:4o(4+1)6d
6:6o(3+1)7n
Instructions
Enter a glycan into the text box as either an IUPAC name, or a structure identifier based on single-letter codes for monosaccharides,
according to the table below. Click the Draw button to draw the structure; (optionally) click Select to choose a knockout
set of enzymes to act on this structure; click React to submit the current structure to Glycologue as a
substrate of the enzymes of N-linked glycosylation. Click Predict to run the enzyme simulator in reverse,
to discover a minimal set of enzymes required to produce the current glycan.
(Example) Enter Galb1-4GlcNAcb1-6[Galb1-4GlcNAcb1-3Galb1-3]GalNAc
or
[L4Y6][L4Y3L3]VT
The anomericity of monosaccharides is implicit, based on the enzymes of N-linked glycosylation: L and Y are β-linked while f, S and V are assumed to be α-linked.
This can be overridden by placing a or b after the sugar symbol, thus La3 would draw an α1,3-linked galactose.
The size of networks produced in simulations can be limited by decreasing the maximum number of GlcNAc residues per glycan using the Control panel. The default value is set to 6.